What note is played on the 1st String at the 1st Fret?

The note played on the 1st string at the 1st fret is F. This is because the 1st string of a guitar is tuned to E in standard tuning, which is the open note. When you press down the string at the 1st fret, you raise the pitch by one semitone. The first note above E is F, thus when you play the 1st string at the 1st fret, you are producing the note F.

In the context of the other notes: G is two semitones above E, A is four semitones above E, and B is six semitones above E. This shows the systematic progression of notes along the fretboard, where each fret corresponds to a half-step increase in pitch. Understanding this concept is essential for navigating the fretboard and recognizing note locations effectively.