What is the note played on the 6th fret of the 2nd string?

The note played on the 6th fret of the 2nd string is a B. The 2nd string on a standard-tuned guitar is the B string, which plays the note B when it is played open (0 fret). Each fret on the guitar represents a half-step increase in pitch. Therefore, moving up to the 1st fret of the 2nd string plays a C note, the 2nd fret plays a C#, the 3rd fret plays a D, the 4th fret plays a D#, and the 5th fret plays an E. Consequently, the note played on the 6th fret is F, making the correct answer not C, but is actually B when played open.

It is crucial to understand how the notes are laid out along the fretboard, as this knowledge is foundational for both playing and improvising on the guitar. Understanding the relationship between frets and notes enables you to navigate the fretboard more effectively, leading to better musical expression.